開催日 | 2021年4月21日(水) |
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開催地 | Web |
【開催日時】 2022年4月21日(水) 12:30~1:30(60分間)※夜の時間帯となります
【参加費】 無料(事前登録制)
【受講方法】 オンライン
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トピック:
ペプチドの精製は、特に多種多様な物理化学的特性を有するペプチドライブラリーでは困難な作業です。 Peptide Easy Clean(PEC)テクノロジーは普遍的に適用可能であり、新しいペプチド医薬品の効率的で革新的な製造を可能にします。
Purification of peptides is a challenging task, especially of diverse peptide libraries, due to their potentially broad distribution in physico-chemical properties. The Peptide Easy Clean (PEC) technology is universally applicable and enables the efficient and innovative manufacturing of new peptide based drug modalities.
PEC increases the speed of peptide development since it can be used for parallel purifications, whereas high-pressure liquid chromatography (HPLC) only allows one-by-one processing of single samples. In addition, PEC is an orthogonal approach to chromatographic separation, facilitating the purification of difficult peptides; by using PEC methodology, aggregation or precipitation can be prevented and increased solubility in organic solvents is achieved.
As a result of our continued collaboration, development of the linker molecules was achieved by Belyntic, with Bachem assisting as an industry partner for early testing on pharmaceutically relevant peptides.
Our combined desire to innovate peptide manufacturing demonstrates that Bachem is the optimum partner for API development, closely supported by Belyntic for all PEC requirements.
スピーカー:
Robert Zitterbart, Ph.D.
Co-Founder, Head of R&D at Belyntic GmbH
The Peptide Easy Clean (PEC) Technology
モデレーター:
Gavin Noble, Ph.D.
R&D Chemist at Bachem (UK) Ltd.
Traceless parallel peptide purification by a first-in-class reductively cleavable linker system featuring a safety-release.
*本プレゼンテーションの言語は英語になります。