スタンダード・バイオツールズ株式会社
Bridging the Gap: Insights from Mouse and Human Models in Pancreatic Cancer Research
2024/12/23
| 開催日 | 2025年1月23日(木) |
|---|---|
| 開催地 | Web |
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a complex tumor microenvironment (TME), that plays a pivotal role in disease progression and resistance to therapy. Investigating the spatial distribution and interaction of TME cells with the tumor is the basis for understanding the mechanisms underlying disease progression and represents a current challenge in PDAC research.
In this webinar you'll learn
How Imaging Mass Cytometry™ (IMC™) technology can be used to assess the abundance, distribution and phenotypes of cells involved in PDAC progression in different precliincal transplanted and genetic murine disease models
How IMC was used to analyze 8 human PDAC tissues, to provide information on the cellular constituents of PDACs and related molecular pathways, specifically capable of characterizing 19 different cancer-associated fibroblast clusters
How integrating mouse and human model analyses provide a comprehensive understanding of tumor-immune-stroma interactions, bridging the gap between preclinical and clinical research to inform future therapeutic strategies
